Zn(OAc)2•2H2O: An efficient catalyst for the one-pot synthesis of 2-substituted benzothiazoles

Communication

JOURNAL 2618

Organic Communications

VOLUME & ISSUE

Year: 2022 Issue: 4 October-December

PAGES

p.378 - 385

DOI ADDRESS

http://doi.org/10.25135/acg.oc.140.2210.2618

STATISTICS

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AUTHORS

Kokane Balaji Digambar
Ravi Varala
Venkata Adilakshmi Gaddaguti

GRAPHICAL ABSTRACT

ABSTRACT

By condensation from aldehyde and 2-aminothiophenol at 80 0C, environmentally friendly, easily accessible, and inexpensive Zn(OAc)2.2H2O (5 mol%) was used to synthesize electronically and structurally divergent benzothiazoles in moderate to good yields (67-96%). All the 2-substituted benzothiazole analogues were thoroughly characterized by IR, NMR and mass spectral analyses.

KEYWORDS

Catalysis
aldehydes
2-aminothiophenol
benzothiazoles
zinc acetate
solvent-free condition

SUPPORTING INFORMATION

Supporting Information

Download File A6-140-OC-2210-2618-SI.pdf (1.28 MB)