JOURNAL 415
Records of Natural Products
Year: 2011 Issue: 3 July-September
p.184 - 192
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Hossein Nazemiyeh, F. Lotfipoor, Abbas Delazar, Seyed M. Razavi, Solmaz Asnaashari, N. Kasebi, A-H. Talebpour, Lutfun Nahar and Satyajit D. Sarker
GRAPHICAL ABSTRACT
ABSTRACT
The composition of the essential oils obtained from the flowering aerial parts of two populations of Thymus pubescens, collected from Mishov-Dagh, was determined by the GC-MS analyses. A total of 18 compounds, representing about 95% of the total oils, were identified in both samples of the essential oils. The essential oils of these two populations showed the presence of high amounts of citronellol (42.0% and 42.6%), geranyl acetate (14.0 and 14.0%), geraniol (13.0 and 13.1%), citronellyl acetate (3.9 and 3.8%), L-linalool (7.8% and 7.9%), cis-nerodiol (5.9% and 5.5%) and citronellyl acetate (3.9% and 3.8%). However, in the published literature, carvacrol, thymol and p-cymene were reported to be the major compounds in T. pubescens. This significant difference in the composition of the essential oils was a clear evidence of chemical polymorphism with in the T. pubescens taxon, suggesting that these two populations of T. pubescens were in deed a new chemotype of this species, and the name Thymus pubescens Boiss. & Kotschy ex Celak chemotype Citronellol for this new chemotype has been proposed . The antibacterial and free-radical-scavenging properties of the essential oils of T. pubescens have also been evaluated.
KEYWORDS- Thymus pubescens
- Lamiaceae
- chemotype
- essential oil
- citronellol
- DPPH
- antibacterial activity