JOURNAL 653


Records of Natural Products
VOLUME & ISSUE
Year: 2013 Issue: 2 April-June
PAGES
p.133 - 136
STATISTICS
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GRAPHICAL ABSTRACT


ABSTRACT


A catecholate type of iron chelator (siderophore); 2,3-dihydroxybenzoyl glycine (DHBG) was produced by Bacillus sp. under i ron stress conditions. Pure DHBG was subjected for DPPH ( α,α−Diphenyl−β− Picrylhydrazyl ) radical scavenging activity and radical induced DNA cleavage inhibition assay. In results, DHBG showed the highest radical scavenging effect and DNA cleavage inhibition activity when it was free from iron. This study revealed antioxidative potential of iron chelator DHBG; and its probable mechanism.

KEYWORDS
  • Catechol
  • 2
  • 3-dihydroxybenzoyl glycine
  • Bacillus sp.
  • DPPH radical
  • Iron