JOURNAL 739


Records of Natural Products
VOLUME & ISSUE
Year: 2014 Issue: 3 July-September
PAGES
p.242 - 261
STATISTICS
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AUTHORS
    Gulmira Özek, Yerlan Suleimen, Nurhayat Tabanca, Roman Doudkin, Petr G. Gorovoy, Fatih Göger, David E. Wedge, Abbas Ali, Ikhlas A. Khan and Kemal Hüsnü C. Başer
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Artemisia argyiA. feddeiA. gmeliniiA. manshurica, and A. olgensis (Asteraceae) were collected in Far East Russia. Oils were hydrodistilled and simultaneously analyzed by GC-FID and GC/MS. Main constituents were found as follows in Artemisia oils: selin-11-en-4 a -ol (18.0%), 1,8-cineole (14.2.0%), artemisia alcohol (12.9%), borneol (9.7%) in A. argyi; camphor (31.2%), 1,8-cineole (17.6%), a -thujone (5.7%) in A. feddei; longiverbenone (12.0%), isopinocamphone (8.9%), 1,8-cineole (6.7%), camphor (5.8%), trans-p-menth-2-en-1-ol (5.3%) in A. gmelinii; germacrene D (11.2%), rosifoliol (10.1%), caryophyllene oxide (6.8%), eudesma-4(15),7-dien-1 b -ol (5.6%) in A. manshurica; eudesma-4(15),7-dien-1 b -ol (6.9%), caryophyllene oxide (5.6%), guaia-6,10(14)-dien-4 b -ol (5.1%) and hexadecanoic acid (5.0%) in A. olgensis. Oils were subsequently submitted for antifungal and antimosquito evaluations. Artemisia species oils showed biting deterrent effects in Aedes aegypti and Artemisia gmelinii oil with the most active biting deterrence index values of 0.82 ± 0.1 at 10 m g/mL. Larval bioassay of A. gmelinii and A. olgensis oils showed higher larvicidal activity against Ae. aegypti larvae with LD50 values of 83.8 (72.6 – 95.7) ppm and 91.0 (73.8 – 114.5) ppm, respectively. Antifungal activity was evaluated against the strawberry anthracnose-causing fungal plant pathogens Colletotrichum acutatumC. fragariae and C. gloeosporioides using direct overlay bioautography assay and all showed non-selective weak antifungal activity. Antioxidant evaluations of the oils were performed by using b -carotene bleaching, Trolox equivalent and DPPH tests. The tested Artemisia oils demonstrated moderate antioxidant activity.

KEYWORDS
  • Artemisia
  • essential oil
  • antifungal
  • botanical insecticidal
  • mosquito control
  • antioxidant activity.