JOURNAL 2492


Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 2-March-April
PAGES
p.363 - 366
STATISTICS
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AUTHORS
  • Wen-Ting Yang
  • Wei Gao
  • Jin-An Liu
  • Xiao-Xiao Liu
  • Lin-Chuan Jia
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new carotane sesquiterpene, trichocarotin N (1), was isolated from the culture of marine-derived fungus Trichoderma virens QD-11. Its structure was established by detailed analysis of 1D/2D NMR and HRESIMS data. Trichocarotin N (1) exhibited moderate cytotoxicity against HeLa and MCF-7 cancer cell lines, with IC50 values of 32.4 and 41.6 μM, respectively.

KEYWORDS
  • Trichoderma virens
  • carotane sesquiterpeneT
  • secondary metabolites
  • cytotoxic activity

SUPPORTING INFORMATION


Supporting Information
Download File 349-RNP-2206-2492-SI.pdf (949.25 KB)