JOURNAL 2875
Records of Natural Products
VOLUME & ISSUE
Year: 2024 Issue: 1 January-February
Year: 2024 Issue: 1 January-February
PAGES
p.155 - 160
p.155 - 160
STATISTICS
Viewed 780 times.
Viewed 780 times.
GRAPHICAL ABSTRACT
ABSTRACT
A new alkaloid called Litsine E (1) and three known aporphine alkaloids (2-4) were isolated from Litsea glutinosa. The structure of the new compound was established using spectroscopic techniques such as HMBC, HSQC, COSY, NOESY, and HRESIMS. Electronic circular dichroism (ECD) calculations were used to estimate its absolute configuration. Subsequently, the newly identified compound was evaluated for its potential to attenuate palmitate-induced viability, demonstrating a significant increase in viability in MIN6 cells.
KEYWORDS- Litsea glutinosa
- aporphine alkaloids
- palmitate-induced viability