A New Alkaloid Glycoside from the Stems of Zanthoxylum dissitum Hemsl.
Records of Natural Products
Available Online: July 30,2020
p.1 - 6
http://doi.org/10.25135/rnp.191.20.05.1643 (DOI number will be activated after the manuscript has been available in an issue.)
Viewed 77 times.
PDF OF ARTICLE
A new alkaloid glycoside (1) and six known alkaloids (2–7) were isolated from the stems of Zanthoxylum dissitum Hemsl.. The structure of compound 1 was resolved by spectrum data, including MS, IR, UV, and MS. All compounds obtained in this research were evaluated for their inhibitions against NO release from LPS-activated RAW264.7 macrophages. Compounds 1-3, 6 and 7 showed significant inhibition activities with IC50 values of 26.12±0.81, 8.41±0.23, 13.75±0.54, 6.97±0.77, and 5.78±0.42 μM, respectively.
- Zanthoxylum dissitum Hemsl.