JOURNAL 3209
Records of Natural Products
Available Online: September 03,2024
p.1 - 6
http://doi.org/10.25135/rnp.473.2404.3209 (DOI number will be activated after the manuscript has been available in an issue.)
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GRAPHICAL ABSTRACT
ABSTRACT
This study aimed to modify the essential oils of Cymbopogon flexuosus (Nees ex Steud.) W.Watson, hereafter referred to as CF, and Cymbopogon martini (Roxb.) W.Watson, hereafter referred to as CM, utilizing an acid-distillation protocol. The modification resulted in a significant reduction in the aldehyde components, Neral and Geranial, in CF, subsequently leading to the formation of the monoterpene, Cymene. Conversely, the alteration in CM decreased the proportions of the monoterpenol, Geraniol, and the ester, Geranyl acetate. These modifications enhanced the cellular safety of both CF and CM essential oils towards B16-F10 cells in vitro, increasing it by 4 to 8-fold, and concurrently improved their melanin suppression and antioxidant properties.
KEYWORDS- Essential Oil Safety
- Acid-distilled
- Whitening
- Antioxidant
