JOURNAL


Records of Natural Products
VOLUME & ISSUE
Available Online: November 15,2018
PAGES
p.1 - 8
DOI ADDRESS
http://doi.org/10.25135/rnp.107.18.09.952
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Seda Fandaklı
  • Nurettin Yaylı
  • Nuran Kahriman
  • Emel Uzunalioğlu
  • Nevin Ulaş Çolak
  • Sercan Yıldırım
  • Ahmet Yasar
  • 1 - Avrasya Üviversitesi
  • 2 - Karadeniz Technical University, Faculty of Pharmacy,61080, Trabzon, Türkiye
  • 3 - Karadeniz Teknik Üniversitesi
  • 4 - Recep Tayyip Erdoğan Üniversitesi
  • 5 - Karadeniz Teknik Üniversitesi
  • 6 - Karadeniz Teknik Üniversitesi
  • 7 - Karadeniz Teknik Üniversitesi
PDF OF ARTICLE

ABSTRACT


The aim of this research was to investigate the effect of different extraction methods on yield and chemical composition of essential oil from Rhododendrum caucasium. The volatiles of R. caucasicum have been isolated by hydro distillation (HD) and solid phase microextraction (SPME). The compositions of the essential oils were characterized by GC-FID and GC-MS. By HD and SPME, a total of twenty-five and thirty-one compounds were identified constituting over 89.25 %, and 90.33 % of oils composition, respectively. The main constituents of R. causacium were found to be calarene with ratios 46.13 % (HD), 54.91 (SPME) and sandaracopimaradine with ratios 25.93 % (HD), 8.16 % (SPME). In addition, the antimicrobial activity of isolated essential oils and obtained methanol and hexane extracts of plant formed the last part of study. According to results, HD essential oil showed moderate antimicrobial activities against Staphylococcus aureus, Enterococcus faecalis, Bacillus cereus and Mycobacterium smegmatis. But other extracts showed not good antimicrobial activities.

KEYWORDS
  • Rhododendron caucasicum; hydrodistillation; SPME; essential oil; antimicrobial activity; GC-FID/MS.