Two New Lignans from Lycopodium japonicum Thunb.
Records of Natural Products
Available Online: April 29,2019
p.1 - 7
http://doi.org/10.25135/rnp.126.19.03.1205 (DOI number will be activated after the manuscript has been available in an issue.)
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Two new lignans, named lycojaponicumoside A (1) and B (2), together with four known compounds (3˗6) were isolated from the n-BuOH extract of Lycopodium japonicum. Their structures were elucidated on the basis of extensive spectroscopic methods, especially various NMR techniques, HRESIMS and circular dichroism (CD). The absolute configuration of compound 1 was established by the calculation of electronic circular dichroism (ECD) curves. All of the compounds were evaluated for their cytotoxic activities against A549 and HepG2 human cancer cell lines, but those compounds did not exhibit cytotoxicity.KEYWORDS
- Lycopodium japonicum
- ECD calculation