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An improved process for eszopiclone: Anti-insomnia agent

Original Article

JOURNAL 139

Organic Communications
VOLUME & ISSUE
Year: 2008 Issue: 2 April-June
PAGES
p.33 - 38
STATISTICS
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AUTHORS
    Kandala S. Charyulu, Chinta R. Reddy, Kisara Satyanarayana, Mandava V. N. B. Rao, V.V.N.K. Prasad Raju, Adla V. Kumar, Virumudi H. Bindu, Vijayavitthal T. Mathod, Apurba Bhattacharyaand Rakeshwar Bandichhor,
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GRAPHICAL ABSTRACT

ABSTRACT

Application of stable hydrochloride salt of 1-chlorocarbonyl-4-methylpiperzine 2 and tetrabutyl ammonium bromide (TBAB) as a phase transfer catalyst in an improved process of eszopiclone 1 is presented.

 KEYWORDS
  • Zopiclone
  • phase transfer catalyst
  • resolution