JOURNAL 143


Organic Communications
VOLUME & ISSUE
Year: 2008 Issue: 3 July-September
PAGES
p.62 - 68
STATISTICS
Viewed 1909 times.
AUTHORS
    Norah Bennamane, Rachedine Kaoua, Lamouri Hammal and Bellara Nedjar-Kolli,
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GRAPHICAL ABSTRACT


ABSTRACT


High-yielding syntheses of two unpublished series of amino-1,5-benzodiazepines derivatives 3 and 1,2,3-benzotriazoles 4 bearing a dimedone moiety are respectively reported. Derivatives were obtained by intramolecular cyclisation using cyanogenbromide of enaminone 2. On the other hand, when enaminones were treated with sodium nitrite under acidic conditions, cyclisation led to benzotriazole 4.

KEYWORDS
  • Dimedone
  • benzotriazoles
  • benzodiazepines
  • cyanobromide
  • enaminones.