JOURNAL 145


Organic Communications
VOLUME & ISSUE
Year: 2008 Issue: 4 October-December
PAGES
p.76 - 83
STATISTICS
Viewed 1888 times.
AUTHORS
    Jihillu. S. Yadav, Basi. V. Subba Reddy, Kaltela S. Shankar, Kokku Premalatha,
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GRAPHICAL ABSTRACT


ABSTRACT


A variety of β-acetamido ketones and ketoesters are readily prepared in high yields under extremely mild conditions via a three component coupling of aromatic aldehydes, enolizable ketones or β-ketoesters and nitriles in the presence of 10 mol% of copper(II) tetrafluoroborate and a stoichiometric amount of acetyl chloride. A solution of 10 mol% of Cu(BF 4) 2 in acetonitrile provides a convenient reaction medium to carry out a three component reaction under mild conditions

KEYWORDS
  • β-Acetamido carbonyl compounds
  • aromatic aldehydes
  • enolizable ketones
  • copper(II) tetrafluoroborate