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B-Oxo anilides in heterocyclic synthesis: Synthesis of tri- and tetracyclic heteroaromatic containing a bridgehead nitrogen atom.

Original Article

JOURNAL 155

Organic Communications
VOLUME & ISSUE
Year: 2009 Issue: 3 July-September
PAGES
p.66 - 71
STATISTICS
Viewed 1886 times.
AUTHORS
    Abdel H. M. Hussein, Mohamed S. El-Gaby, Fathi Abu-Shanab and Mohamed A. M. Abdel-Raheim
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

New heterocyclic compounds were synthesized using N-(benzo[d]thiazol-2-yl)-3-oxobutanamide (1) as starting material. The condensation of 1 with DMF-DMA by refluxing in xylene gave 3-Acetyl-2H-pyrimido[2,1-b][1,3]benzothiazol-2-one (3). Compound 3 was reacted with 2-cyanoethanethioamide, malononitrile, malononitrile/S, phenylhydrazine, and hydrazine  to give new azoloazine derivatives

 KEYWORDS
  • Pyrimido[2
  • 1-b][1
  • 3]benzothiazol-2-one
  • benzo[d]pyrido[2'
  • 3':4
  • 5]pyrimido[2
  • 1-][1
  • 3]thiazole-3-carbonitrile
  • pyrazolo[3'
  • 4':4
  • 5]pyrimido[2
  • 1-b][1
  • 3] thiazole