Synthesis, spectral and antimicrobial activity of [3-(4-chloro-phenoxy)-2,4-diisopropyl)-2,3,4,5-tetrahydro-1H-3l5-benzo[e][1,3,2]diazaphosphepin-3-ylidene]-alkyl-amine (Staudinger reaction)

Original Article

JOURNAL 159

Organic Communications

VOLUME & ISSUE

Year: 2009 Issue: 4 October-December

PAGES

p.120 - 127

STATISTICS

Viewed 1879 times.

AUTHORS

Ch. Mohan, A. Janardhan Rao, C. Naga Raju and R. Usha Nagalakshmi

GRAPHICAL ABSTRACT

ABSTRACT

3-(4-chlorophenoxy)-2,4-diisopropyl-2,3,4,5-tetrahydro-1H-benzo[e][1,3,2]diaza-phosphepine was synthesized starting from 1,2-bis(bromomethyl)benzene by reacting with 2 equimolar isopropyl amine, one equimolar PBr3 and then one equimolar 4-chlorophenol, respectively. The Staudinger reaction of the diazaphphosphine with a series of alkyl azides gave the corresponding iminophosphoranes. Antibacterial activities of the synthesized iminophosphoranes were screened

KEYWORDS

Iminophosphoranes
1
2-bis(bromomethyl)benzene
Isopropylamine
phosphorus tribromide
4-chlorophenol
alkyl azides