Condensation of 3-Aza-1, 5-Diketones with N-Nucleophiles

Original Article

JOURNAL 166

Organic Communications

VOLUME & ISSUE

Year: 2010 Issue: 4 October-December

PAGES

p.76 - 83

STATISTICS

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AUTHORS

Gurusamy Ravindran Nedumaram Gopalan Renganathan

GRAPHICAL ABSTRACT

ABSTRACT

The reaction of substituted diphenacyl anilines with ammonium acetate under microwave irradiation afforded 1,3,5-triaryl-1,2-dihydropyrazines. In the present paper the use of microwave irradiation allows to improve the yields and expedite the reaction. Phenylhydrazine is used as nitrogen nucleophile. The reaction pathways of prepared compounds are discussed in detail in this paper.

KEYWORDS

Diphenacyl anilines
nucleophiles
dihydropyrazines
ammonium acetate
phenylhydrazine