Synthesis and biological activity of 2-oxo-azetidine derivatives of phenothiazine

Original Article

JOURNAL 179

Organic Communications

VOLUME & ISSUE

Year: 2011 Issue: 2 April-June

PAGES

p.42 - 51

STATISTICS

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AUTHORS

Sharma Ritu, Samadhiya Pushkal, Srivastava S. D. and Srivastava S. K.

GRAPHICAL ABSTRACT

ABSTRACT

We have synthesized of N-[2-(10H-phenothiazinyl)ethyl]-4-(phenyl)-3-chloro-2-oxo-1-iminoazetidine 4(a-m). The structures of all the newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR and FAB-Mass and chemical methods. All synthesized compounds were evaluated for their antibacterial, antifungal and antitubercular activity which displayed acceptable results.

KEYWORDS

Synthesis
biological activity
2-azetidinone
phenothiazine.