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Synthesis and characterization of new analogs of zafirlukast

Original Article

JOURNAL 189

Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 1 January-March
PAGES
p.27 - 41
STATISTICS
Viewed 2361 times.
AUTHORS
    Gilla Goverdhan , Anumula Raghupathi Reddy, N. Rama Krishna Reddy 1, Kurella Srinivas, Vurimidi Himabindu and Ghanta Mahesh Reddy
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GRAPHICAL ABSTRACT

ABSTRACT

Design, synthesis and characterization of four novel series of Zafirlukast analogs are described. The modifications are substitution on indole nitrogen, C-5 position of indole moiety and amide nitrogen of zafirlukast.

 KEYWORDS
  • Zafirlukast
  • anti asthma
  • new analogs
  • N-desmethyl zafirlukast analogs
  • DCU analogs.