p-Dimethylaminopyridine (DMAP): A highly efficient catalyst for one pot, solvent free synthesis of substituted 2-amino-2-chromenes under microwave irradiation
Year: 2012 Issue: 4 October-December
p.179 - 185
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Kamlesh R. Desale , Kamalakar P. Nandre and Shamkant L. Patil
A highly efficient, green and expeditious method is described for the synthesis of substituted 2-amino2-chromenes employing one pot three component condensation of aromatic aldehydes, malononitrile and activated phenol in presence of p-dimethylaminopyridine (10 mol %) as a catalyst under microwave irradiation. The present method is operationally simple and offers many advantages such as high yield, short reaction time and simple workup.KEYWORDS
- microwave irradiation.