JOURNAL 1722
Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 4 October-December
Year: 2012 Issue: 4 October-December
PAGES
p.179 - 185
p.179 - 185
STATISTICS
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Viewed 1819 times.
GRAPHICAL ABSTRACT
ABSTRACT
A highly efficient, green and expeditious method is described for the synthesis of substituted 2-amino2-chromenes employing one pot three component condensation of aromatic aldehydes, malononitrile and activated phenol in presence of p-dimethylaminopyridine (10 mol %) as a catalyst under microwave irradiation. The present method is operationally simple and offers many advantages such as high yield, short reaction time and simple workup.
KEYWORDS- 2-amino-2-chromenes
- multicomponent
- p-dimethylaminopyridine
- microwave irradiation.