A facile one-pot synthesis of 3-(1-Benzyl-2-phenyl-1H-imidazol-4-yl)-4-hydroxy-6-methyl-2H-pyran-2-one derivatives via multi-component approach

Original Article

JOURNAL 679

Organic Communications

VOLUME & ISSUE

Year: 2014 Issue: 2 April-June

PAGES

p.53 - 59

STATISTICS

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AUTHORS

Thirupaiah Bade and Rajeswar Rao Vedula

GRAPHICAL ABSTRACT

ABSTRACT

A one pot, four component synthesis of 1, 2, 4-trisubstituted imidazoles is described by reacting a mixture of bromo dehydroacetic acid, aromatic aldehyde, benzyl amine, and ammonium acetate in dry alcohol. All the synthesized compounds were characterized by their analytical and spectral data.

KEYWORDS

bromo dehydroacetic acid
aromatic aldehyde
benzyl amine
ammonium acetate
imidazole
one-pot