JOURNAL 688


Organic Communications
VOLUME & ISSUE
Year: 2014 Issue: 4 October-December
PAGES
p.130 - 136
STATISTICS
Viewed 2036 times.
AUTHORS
    Chandramouleswararao Jillepalli, Praveen Kumar Bonkuri and Madhukar Jeripothula
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A simple and efficient protocol has been developed for the synthesis of Hantzsch pyridines. In the reported synthesis, a variety of aldehydes undergo smooth condensation reaction with ethyl acetoacetate and ammonium acetate in presence of Germanium (IV) iodide in acetonitrile. This method is applicable to a variety of substrates to afford the corresponding 1,4-dihydropyridines in one-pot reaction in excellent yields.

KEYWORDS
  • Aldehydes
  • diketones
  • ammonium acetate
  • GeI 4
  • 1
  • 4-Dihydropyridine