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Amberlyst-15: An Efficient and reusable heterogeneous catalyst for the synthesis of β-amino carbonyl compounds

Original Article

JOURNAL 777

Organic Communications
VOLUME & ISSUE
Year: 2015 Issue: 4 October-December
PAGES
p.90 - 97
STATISTICS
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AUTHORS
    Pathakota Venkata Ramana, Kunda Uma Maheswara Rao, Balam Satheesh Krishna, Soora Harinath Jayaprakash, Shaik Ahammed Kabeer, Kaveti Sudheer and Cirandur Suresh Reddy
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GRAPHICAL ABSTRACT

ABSTRACT

A simple and efficient method has been developed for the synthesis of β-amino carbonyl compounds from aromatic ketones, aldehydes and amines by Mannich reaction in the presence of amberlyst-15 as a reusable heterogeneous catalyst at room temperature under solvent-free conditions. The noteworthy advantages of the present method are short reaction times, good product yields, simple procedures and use of non-toxic catalyst.

 KEYWORDS
  • β -Amino carbonyl compounds
  • Amberlyst-15
  • Mannich reaction