Simple synthesis of non-symmetric 1,4-dialkoxybenzenes via 4-alkoxyphenols

Original Article

JOURNAL 782

Organic Communications

VOLUME & ISSUE

Year: 2016 Issue: 1 January-March

PAGES

p.23 - 31

STATISTICS

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AUTHORS

Motyka Radosław, Stecko Sebastian and Suwiński Jerzy W.

GRAPHICAL ABSTRACT

ABSTRACT

A three steps synthesis of non-symmetric 1,4-dialkoxybenzenes starting from 4-hydroxybenzaldehydes was described. At first step 4-alkoxyphneols were alkylated to give 4-alkoxybenzaldehydes. At the second step 4-alkoxybenzaldehydes were submitted to a Baeyer-Villiger oxidation with 30% H 2O 2 to afford 4-alkoxyphenols. At the last step 4-alkoxyphenols were secondly alkylated to give the title compounds.

KEYWORDS

4-alkoxyphenols
1
4-dialkoxybenzenes
monomer
PPV
synthesis