Synthesis and characterization of novel mono, bis and tris heteroaryl chalcone derivatives of 1,3,5-trimethoxybenzene

Original Article

JOURNAL 1942

Organic Communications

VOLUME & ISSUE

Year: 2021 Issue: 1 January-March

PAGES

p.39 - 47

DOI ADDRESS

http://doi.org/10.25135/acg.oc.95.21.01.1942

STATISTICS

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AUTHORS

M. Fatih Polat
Derya Aktaş Anıl

GRAPHICAL ABSTRACT

ABSTRACT

In this study, a new series consisting of 12 heteroaryl chalcone derivatives of 1,3,5-trimethoxybenzene were synthesised. Chalcones were synthesised in high purity and efficiency, via condensation of mono, bis and tris 2,4,6-trimethoxy acetophenones with hetero-2-carbaldehyde derivatives based on Claisen Schdmit condensation. The reactions feature a good scope for the all products, mild reaction conditions and good yields. The synthesized compounds were characterized by using FT-IR, NMR and elemental analysis spectroscopic techniques.

KEYWORDS

Heteroaryl
chalcone
synthesis
characterization

SUPPORTING INFORMATION

Supporting Information

Download File A2-95-OC-2101-1942-SI.pdf (1.17 MB)