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Chemical Investigation of Euphorbia schimperi C. Presl

Original Article

JOURNAL 13

Records of Natural Products
VOLUME & ISSUE
Year: 2008 Issue: 2 April-June
PAGES
p.39 - 45
STATISTICS
Viewed 3111 times.
AUTHORS
    Azza R. Abdel-Monem, Essam Abdel-Sattar, Fathalla M. Harraz, and Frank Petereit
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Three triterpenoids; cycloart-25-en-3β,24-diol, cycloart-23-en-3β,25-diol, and a -amyrin, in addition to b -sitosterol- b -D-O-glucoside, scopoletin, luteolin and kampferol were isolated for the first time from the chloroform fraction of the alcoholic extract of Euphorbia schimperi C. Presl (F. Euphorbiaceae). The isolated compounds were identified using different spectroscopic methods (EIMS, 1HNMR, 13CNMR, HMQC, HMBC and COSY). The cytotoxic activity of the chloroform fraction was also studied using brain and breast carcinoma cell lines.

 KEYWORDS
  • Euphorbia schimperi
  • triterpenoids
  • cycloartane
  • b -sitosterol- b -D-O-glucoside
  • scopoletin
  • luteolin
  • kampferol
  • cytotoxic activity.