Kitasatodine and Kitasatopenoid from Kitasatospora sp. H6549, a New Strain from Malaysia

Original Article

JOURNAL 513

Records of Natural Products

VOLUME & ISSUE

Year: 2012 Issue: 4 October-December

PAGES

p.1 - 5

STATISTICS

Viewed 2358 times.

AUTHORS

Niuniu Shi, Chunhua Lu, Coy Choke Ho, and Yuemao Shen

A new pyridine-containing natural product, kitasatodine (1), and a new sesquiterpene, kitasatopenoid (2), together with a known cycloheximide (3) were isolated from the ethyl acetate extract of the strain H6549 (Kitasatospora sp.), which was isolated from dipterocarp forest of Kepong Kuala Lumpur in Malaysia. Their structures were established by spectroscopic methods including 1D and 2D-NMR experiments and HR-Q-TOF-MS. In addition, compounds 1and 2 showed moderate cytotoxicity against HeLa and HepG-2 cell lines.

KEYWORDS