JOURNAL 524


Records of Natural Products
VOLUME & ISSUE
Year: 2013 Issue: 1 January-March
PAGES
p.27 - 34
STATISTICS
Viewed 1164 times.
AUTHORS
    Yu-Chang Su and Chen-Lung Ho
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


This study investigated the chemical composition, and antimicrobial and anti -wood-decay fungal activities of the essential oil isolated from the leaf of Litsea acuminata (Blume) Kurata from Taiwan. The essential oil from the fresh leaves of L.acuminata was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC–FID and GC–MS. A total of 48 compounds were identified, representing 100% of the oil. The main components identified were b -caryophyllene (13.0%), t -cadinol (11.1%), a -cadinol (8.6%), α-humulene (7.5%), a -pinene (7.0%), globulol (6.6%), and b -eudesmol (6.1%) . The antimicrobial activity of the oil was tested by the disc diffusion method and micro-broth dilution method against ten microbial species, respectively. The oil exhibited strong growth suppression against Gram-positive bacteria and yeast with inhibition zones of 4 5~ 50 mm to MIC values of 31.25~62.5 μg / mL, respectively. The anti-wood-decay fungal activity of the oil was also evaluated. Results showed that the oil demonstrated excellent activity against four wood-decay-fungi species. For the antimicrobial and anti-wood-decay fungal activities of the oil, the active source compounds were determined to be t -cadinol, a -cadinol, and b -eudesmol.

KEYWORDS
  • Litsea acuminate
  • Lauraceae
  • essential oil
  • antimicrobial activit y
  • anti -wood-decay fungal activit y
  • t -cadinol