A New Compound Along With Seven Known Compounds from an Endophytic Fungus Aspergillus sp. HS-05

 Investigation of EtOAc extract from the fermentation broth of the endophytic fungus Asperilligus sp. HS-05 led to the isolation of a new compound (1) of spiro moiety named aspergispiroketal and seven known compounds (2-8). Their structures were elucidated mainly by NMR and HR-TOF-MS, as well as on comparison with the reported data. The absolute configuration of 1 was defined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra.