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A New Cytotoxic Alkenylresorcinol from Embelia schimperi

Short Report

JOURNAL 711

Records of Natural Products
VOLUME & ISSUE
Year: 2014 Issue: 1 January-March
PAGES
p.37 - 40
STATISTICS
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AUTHORS
    Blanche L. Ndontsa, Faustine L. M. Dongmo, Michel F. Tala, Hippolyte K. Wabo, Guang-Zhi Zeng, Ning-Hua Tan and Pierre Tane
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GRAPHICAL ABSTRACT

ABSTRACT

An investigation of MeOH extract of Embelia schimperi stem led to the isolation of a new resorcinol derivative, 5-(7’Z-pentadecenyl)resorcinol (1), along with the known compounds lupeol (2) and β-sitosterol glucoside (3). The structures of isolated compounds were elucidated using spectroscopic methods. Compound 1 exhibited moderate in vitro cytotoxic activity against human Hela cell line.

 KEYWORDS
  • Embelia schimperi
  • Myrsinaceae
  • alkenylresorcinol
  • 5-(7’Z-pentadecenyl)resorcinol
  • cytotoxic activity.