JOURNAL 546


Records of Natural Products
VOLUME & ISSUE
Year: 2015 Issue: 3 July-September
PAGES
p.323 - 328
STATISTICS
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AUTHORS
    Liangliang Gao, Xiaoqian Liu, Chun Li, Zhimin Wang and Tao Guo
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GRAPHICAL ABSTRACT


ABSTRACT


A secoiridoid glucoside dimer derivative, named as 4', 5'-(2'-hydroxy ligustrosidic acid) dimer (1), together with two known secoiridoids were isolated from the aqueous extract of Ligustri lucidi fructus. Structures of these compounds were elucidated by analysis of spectroscopic data including 1D-, 2D-NMR and HR-ESI-MS, and the reported literature data comparison. This is the first report on iridoid dimer derivative isolation from the genus Ligustrum. Their antioxidant activities were evaluated by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Compound 1 exhibited moderate antioxidant activity.

KEYWORDS
  • Ligustri lucidi fructus
  • Secoiridoid dimer derivative
  • Antioxidant activity