JOURNAL 566


Records of Natural Products
VOLUME & ISSUE
Year: 2015 Issue: 4 October-December
PAGES
p.496 - 502
STATISTICS
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AUTHORS
    Pınar Kalın, İlhami Gülçin and Ahmet C. Gören
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Cranberries (Vaccinium macrocarpon) contain many bioactive compounds and have some biological activities and beneficial health properties. In the study, antioxidant effects of lyophilized aqueous extract of cranberry (LAEC) and quantity of some its polyphenolic compounds were determined. For this purpose, we performed DPPH·, DMPD •+, ABTS •+ and O 2 •- radicals scavenging activities, inhibition of lipid peroxidation activity by thiocyanate method, Cu 2+ and Fe 3+ reducing abilities, FRAP assay and Fe 2+ binding activity. At the 10 µg/mL concentration, LAEC inhibited 52.4% lipid peroxidation produced by linoleic acid emulsion. Also, α-tocopherol, BHA, trolox, and BHT had 52.5, 89.9, 93.1 and 94.9% inhibition value at 30 µg/mL concentration, respectively. Quantitative amounts of some phenolic compounds in LAEC were investigated by high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). p-Hydroxy benzoic acid was found as the most abundant phenolic compound (55 mg/kg extract) in LAEC.

KEYWORDS
  • Cranberries (Vaccinium macrocarpon)
  • Polyphenol content
  • Radical scavenging
  • Antioxidant activity
  • LC-MS/MS

SUPPORTING INFORMATION


Supporting Information
Download File 60-RNP-1401-284-SI.pdf (462.72 KB)