JOURNAL 612


Records of Natural Products
VOLUME & ISSUE
Year: 2015 Issue: 4 October-December
PAGES
p.572 - 575
STATISTICS
Viewed 1175 times.
AUTHORS
    Farid Khallouki, Khalid Sellam, Rabia Koyun, Irvila Ricarte, Chakib Alem, Lhoussaine Elrhaffari and Robert W. Owen
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


The purpose of this study was to determine the phytochemical content of Cotula cinerea to establish principal components which may consolidate its use as a medicinal plant in the southeast of Morocco. The amount of total phenolic compounds as determined by analytical HPLC in methanol extracts was 79.23 ± 2.5 mg/g dry matter. The major phenolic compounds identified by HPLC-ESI-MS were neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid and luteolin-4´-O-glucoside. All compounds displayed very strong antioxidant capacities in the DPPH, FRAP and ORAC assays . The data indicates that methanol extracts of C. cinerea via their antioxidant capacities, may be effective disease prevention potions in traditional African medicine which is probably related to the significant content of echinoids and flavonoids.

KEYWORDS
  • Cotula cinerea
  • chlorogenic acids
  • flavonoids
  • antioxidant capacity

SUPPORTING INFORMATION


Supporting Information
Download File 71-RNP-1410-203-SI.pdf (215.18 KB)