JOURNAL 593


Records of Natural Products
VOLUME & ISSUE
Year: 2016 Issue: 5 September-October
PAGES
p.645648 - 0
STATISTICS
Viewed 2503 times.
AUTHORS
    Xiaopo Zhang, Mei Gui, Caiyun Zhang, Changyu Chen, Lei Yu and Jie Liu
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new abietane diterpenoid glycoside , leucasinoside , along with two known ones were obtained from the aerial parts of Leucas zeylanica . Its structure was characterized by comprehensive analyses of 1 H , 13 C NMR, COSY, H S QC, HMBC , NOESY spectroscopic, and HREIMS mass spectrometric data. All the isolates were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7, and the new compound showed moderate inhibitory activity.

KEYWORDS
  • Leucas zeylanica
  • abietane diterpenoid
  • leucasinoside
  • anti-inflammatory

SUPPORTING INFORMATION


Supporting Information
Download File 78-RNP-1511-239-SI.pdf (618.25 KB)