JOURNAL 586
Records of Natural Products
VOLUME & ISSUE
Year: 2016 Issue: 5 September-October
Year: 2016 Issue: 5 September-October
PAGES
p.628 - 632
p.628 - 632
STATISTICS
Viewed 2122 times.
Viewed 2122 times.
AUTHORS
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Xin Wu, Hongbo Liao, Xiaohui Zhu, Hongyu Lu, Xiaobin Zeng, Liao Cui, Xiaohua Lv, Yanqun Li and Chaohua Zhang
GRAPHICAL ABSTRACT
ABSTRACT
Two new dammarane triterpenes , cereotagalol C ( 1 ) and cereotagalol D (2 ), were isolated from the leaves of Ceriops tagal. Their structures were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR and HR -ESI -MS. Their cytotoxic activities against A549, HepG2, HCT-116 and CNE-2 cell lines were also evaluated, which revealed that compounds 1 and 2 had selected moderate cytotoxicity against HCT-116 and CNE-2 with IC 50 values of 29.7 and 37.2 μ M, respectively.
KEYWORDS- Dammarane triterpenes
- Ceriops tagal
- spectroscopic analyses
- cereotagalol C
- cereotagalol D
