JOURNAL 633


Records of Natural Products
VOLUME & ISSUE
Year: 2016 Issue: 6 November-December
PAGES
p.818 - 823
STATISTICS
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AUTHORS
    Hamed Shamkhani, Naser Nasiri, Atousa Aliahmadi and Ali Sonboli
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Composition and antibacterial activity of the hydro-distilled essential oil from aerial parts of Tanacetum hololeucum from Iran were investigated. The oil of T. hololeucum was analyzed by GC-FID and GC-MS. The major compounds were found to be artemisia alcohol (22.8%), yomogi alcohol (19.4%), artemisyl acetate (12.9%), γ-eudesmol (12.1%) and camphor (10.5%). The antibacterial activity of the oil was tested against four bacteria (Staphylococcus aureus, Bacillus cereus, KlebsiellaPneumoniae and Escherichia coli) by disk diffusion and determination of MIC and MBC values. The results showed that Gram-positive bacteria were highly inhibited by the oil with MIC values of 2 mg/mL. The most resistant strain was KlebsiellaPneumoniae with the highest MIC and MBC values of 16 and >32 mg/mL, respectively. Considering sensitivity screening it is notable that the antibacterial property of the oil from T. hololeucum could be attributed mainly to the synergistic property of main compounds.

KEYWORDS
  • Tanacetum
  • hydro-distillation
  • yomogi alcohol
  • artemisia alcohol
  • Iran

SUPPORTING INFORMATION


Supporting Information
Download File 98-RNP-1505-028.pdf (480.44 KB)