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Chemical Composition, Enantiomeric Distribution and AChE-BChE Activities of the Essential Oil of Myrteola phylicoides (Benth) Landrum from Ecuador

Original Article

JOURNAL 893

Records of Natural Products
VOLUME & ISSUE
Year: 2019 Issue: 4 July-August
PAGES
p.355 - 362
DOI ADDRESS
http://doi.org/10.25135/rnp.112.18.09.893
STATISTICS
Viewed 2858 times.
AUTHORS
  • James Calva
  • Jessica M Castillo
  • Nicole Bec
  • Jorge Ramirez
  • José Miguel Andrade
  • Christian Larroque
  • Chabaco Armijos
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

The volatile constituents of the essential oil (EO) of Myrteola phylicoides (Benth) Landrum, from Ecuador, extracted by steam distillation have been analyzed. A total of 37 compounds, representing 90.30% the total essential oil sample were identified. Monoterpenes hydrocarbons (53.06%) and sesquiterpene hydrocarbons (35.24%) were the principal groups of compounds. The major components were identified as α-pinene (30.94%), (E)-caryophyllene (21.93%), β-pinene (14.45%) and α-humulene (9.56%). The essential oil of M. phylicoides showed weak in vitro activity against AChE inhibition with IC50 value 60.8 μg/mL and a low BChE activity with IC50 value >250 μg/mL. This is the first report on the chemical composition of the essential oil of this species.

 KEYWORDS
  • Myrteola phylicoides
  • essential oil
  • AChE
  • BChE

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graphical abstract

Graphical abstract for article “Chemical composition, enantiomeric distribution and AChE-BChE activities of the essential oil of Myrteola phylicoides (Benth) Landrum, from Ecuador.”