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A New Heliquinomycin Analogue with Immunosuppressive Activity from Streptomyces sp. jys28

Original Article

JOURNAL 1085

Records of Natural Products
VOLUME & ISSUE
Year: 2019 Issue: 6 November-December
PAGES
p.456 - 461
DOI ADDRESS
http://doi.org/10.25135/rnp.123.18.12.1085
STATISTICS
Viewed 2427 times.
AUTHORS
  • Can Su
  • Chongxi Liu
  • Yongjiang Wang
  • Wen-Sheng Xiang
  • Chenggang Zou
  • Sheng-Xiong Huang
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Heliquinomycin (1) and a new analogue 9′-methoxy-heliquinomycin (2) were isolated from the culture broth of Streptomyces sp. jys28. The structure of new analogue was elucidated by comprehensive analyses of HR-ESI-MS and NMR spectroscopic data. Among them, Heliquinomycin (1) showed immunosuppressive and antibacterial activities.

 KEYWORDS
  • Heliquinomycin
  • Immunosuppressive activity
  • Antibacterial activity

SUPPORTING INFORMATION

Supporting Information
Download File A3-123-RNP-1812-1085-SI.pdf (1.41 MB)