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Two New Compounds from the Deep-Sea-Serived Fungus Aspergillus sp. YPGA8

Short Report

JOURNAL 1487

Records of Natural Products
VOLUME & ISSUE
Year: 2020 Issue: 4 July-August
PAGES
p.307 - 311
DOI ADDRESS
http://doi.org/10.25135/rnp.162.19.11.1487
STATISTICS
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AUTHORS
  • Meng-Hua Pan
  • Zhi-Yong Tian
  • Hui Yang
  • Wei Xu
  • Chen Pan
  • Zhongbin Cheng
  • Qin Li
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Chemical examination of a fraction of the EtOAc extract of a marine-derived fungus Aspergillus sp. YPGA8 resulted in the isolation of two new compounds, namely aspertriols A-B (1-2). Compounds 1-2 possess an identical 2,3,4-trihydroxybutoxy moiety, which is rarely found in natural products. Their structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, HRESIMS). The bioassay study revealed that compounds 1 and 2 were inactive toward a-glucosidase.

 KEYWORDS
  • marine-derived fungus
  • Aspergillus sp. YPGA8
  • aspertriols A-B
  • isolation
  • structure identification

SUPPORTING INFORMATION

Supporting Information
Download File A10-162-RNP-1911-1487-SI.pdf (1.25 MB)