JOURNAL 2039
Records of Natural Products
VOLUME & ISSUE
Year: 2022 Issue: 2 March-April
Year: 2022 Issue: 2 March-April
PAGES
p.110 - 117
p.110 - 117
STATISTICS
Viewed 1617 times.
Viewed 1617 times.
AUTHORS
-
Yue Li
-
Jun Chi
-
Ping Wang
-
Lingxia Zhang
-
Qingxia Li
-
Qingmei Feng
-
Liping Dai
-
Zhimin Wang
GRAPHICAL ABSTRACT
ABSTRACT
A new isoflavonoid glycoside, achyranthoside C (1), along with two known compounds (2 and 3) were isolated from the rhizomes of Achyranthes bidentata. Compounds 1-2 were two rare natural isoflavonoid glycosides with C8 hydroxymethylene derivatization. Their structures were elucidated through comprehensive 1D and 2D NMR, UV, IR, and HRMS analyses. Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.
KEYWORDS- Achyranthes bidentata
- isoflavonoid glycosides
- antioxidant activity
