A New Alkaloid from the Endophytic Fungus of Crocus sativus L., Aspergillus fumigatus Y0107

Original Article

JOURNAL 2235

Records of Natural Products

VOLUME & ISSUE

Year: 2022 Issue: 5 September-October

PAGES

p.463 - 470

DOI ADDRESS

http://doi.org/10.25135/rnp.307.2110.2235

STATISTICS

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AUTHORS

Yu Jiang
Chunxiao Jiang
Qi Zhou
Yingpeng Tong
Ping Wang

GRAPHICAL ABSTRACT

ABSTRACT

A new alkaloid (compound 1), together with 8 known alkaloids (compounds 2-9), were isolated from Aspergillus fumigatus Y0107 extracts from the lateral buds of Crocus sativus Linn (saffron). The structure of compound 1 was elucidated with NMR spectroscopy, High-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and compared with its analogues in the literatures. The antibacterial activities of the crude ethyl acetate (EA) extract (CEE) and isolated compounds (compounds 1, 2, 6, 8) were evaluated against plant pathogenic bacteria. Compound 2 and the CEE demonstrated moderate inhibitory activity with MICs of 100 μg/mL against Erwinia sp.

KEYWORDS

Crocus sativus L.
endophytic fungus
Aspergillus fumigatus Y0107
alkaloids
plant pathogenic bacteria

SUPPORTING INFORMATION

Supporting Information

Download File A7-307-RNP-2110-2235-SI.pdf (1.41 MB)