JOURNAL 2447
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 2-March-April
Year: 2023 Issue: 2-March-April
PAGES
p.352 - 357
p.352 - 357
STATISTICS
Viewed 2128 times.
Viewed 2128 times.
GRAPHICAL ABSTRACT
ABSTRACT
Abstract: The fungal strain Aspergillus fumigatus CBC18132, isolated from deep-sea sediment, was investigated for secondary metabolites. Fermentation on rice medium followed by chromatographic separation led to the isolation of three polyketides (13) and nine alkaloids (413). The structures were determined by analyses of spectroscopic data (1H and 13C NMR, and MS data). The absolute configuration of the anthraquinone-derivative trypacidin was resolved for the first time by a combination of ECD and specific rotation calculation. All isolated compounds were inactive toward the -glucosidase at the initial concentration of 2 mM.
KEYWORDS- Aspergillus fumigatus
- trypacidin
- absolute configuration
