JOURNAL 2685
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 4 July-August
Year: 2023 Issue: 4 July-August
PAGES
p.710 - 714
p.710 - 714
STATISTICS
Viewed 1910 times.
Viewed 1910 times.
GRAPHICAL ABSTRACT
ABSTRACT
A new ingenane diterpenoid, named ingenol-20-laurate (1), and two known analogues (ingenol-20-palmitate (2), ingenol-20-pentadecanoate (3)) and an ent-abietane diterpenoid (euphopilolide, 4) were isolated from the whole plants of Euphorbia jolkinii. The structure of compound 1 was elucidated by HRESIMS and 2D NMR methods. The cytotoxicities of compound 1 against SMMC-7721, MDA-MB-231, and SW480 cell lines were 27.22±0.58, 17.69±0.29 and 16.19±0.77 μM, respectively.
KEYWORDS- Euphorbia jolkinii
- diterpenoids
- cytotoxicities
