JOURNAL 2807
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 6 November-December
Year: 2023 Issue: 6 November-December
PAGES
p.1064 - 1068
p.1064 - 1068
STATISTICS
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Viewed 1681 times.
GRAPHICAL ABSTRACT
ABSTRACT
Herein, the chemical analysis of petroleum ether extract of Eupatorium adenophorum was conducted which led to the identification of a previously unreported sesquiterpenoid, named eupatorione A (1). The structure of eupatorione A (1) was elucidated through comprehensive spectroscopic analysis, including 1D, 2D-NMR techniques, as well as HRMS. Additionally, X-ray diffraction was employed to further confirm the structure. The anti-inflammatory activity of compound 1 was assessed by measuring its inhibitory effects on the production of nitric oxide (NO), induced by lipopolysaccharide (LPS) in RAW264.7 LPS-activated macrophages.
KEYWORDS- Compositae
- Eupatorium adenophorum
- sesquiterpenoid
- chemical structure