JOURNAL 2875


Records of Natural Products
VOLUME & ISSUE
Year: 2024 Issue: 1 January-February
PAGES
p.155 - 160
STATISTICS
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AUTHORS
  • Yuanyuan Zhou
  • Zibao Huang
  • Chenpeng Liu
  • Guoyu Li
  • Xiaopo Zhang
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new alkaloid called Litsine E (1) and three known aporphine alkaloids (2-4) were isolated from Litsea glutinosa. The structure of the new compound was established using spectroscopic techniques such as HMBC, HSQC, COSY, NOESY, and HRESIMS. Electronic circular dichroism (ECD) calculations were used to estimate its absolute configuration. Subsequently, the newly identified compound was evaluated for its potential to attenuate palmitate-induced viability, demonstrating a significant increase in viability in MIN6 cells.

KEYWORDS
  • Litsea glutinosa
  • aporphine alkaloids
  • palmitate-induced viability

SUPPORTING INFORMATION


Supporting Information
Download File A9-427-RNP-2308-2875-SI.pdf (1.92 MB)