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Lyratin D, a New 4-Hydroxyisoflavan from the Whole Plant of Solanum lyratum Thunb

Short Report

JOURNAL 3249

Records of Natural Products
VOLUME & ISSUE
Year: 2024 Issue: 5 September-October
PAGES
p.508 - 513
DOI ADDRESS
http://doi.org/10.25135/rnp.472.2406.3249
STATISTICS
Viewed 849 times.
AUTHORS
  • Nguyen Minh Trang
  • Le Ba Vinh
  • Nguyen Viet Phong
  • Seo Young Yang
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

A new 4-hydroxyisoflavan, named lyratin D (1), was isolated from the whole plant of Solanum lyratum Thunb. Its structure and absolute configuration were elucidated through comprehensive analysis of its HR-ESI-MS, 1D and 2D NMR, and circular dichroism spectroscopy data. Compound 1 was then assessed for its cytotoxic effects on RAW264.7 murine macrophage cells, and its antioxidant activity was evaluated through DPPH assay.

 KEYWORDS
  • Solanum lyratum
  • 4-Hydroxyisoflavan
  • Antioxidant

SUPPORTING INFORMATION

Supporting Information
Download File A4-471-RNP-2406-3249-SI.pdf (2.12 MB)