JOURNAL 3585
Records of Natural Products
Year: 2025 Issue: 6 November-December
p.680 - 687
Viewed 52 times.
GRAPHICAL ABSTRACT
ABSTRACT
It is believed that microalgae biomass can be used in a variety of ways. However, their use is currently limited to specific fields, and there are a few applications of microalgae biomass in drug discovery. Numerous microalgae inhabit the world, and they likely produce unknown substances that contribute to human health. In this study, therefore, we used Haematococcus as a material to search for substances that were beneficial to human health. We tried to identify them using their blood pressure-lowering effect as an indicator, and then we succeeded in isolating two novel substances, saganhaematenone A and B. The structural analysis revealed that they belong to glyceroglycolipid and were analogues with a stereoisomeric relationship. Our findings suggest that microalgae biomass may also have beneficial effects on human health.
KEYWORDS- Haematococcus
- microalgae
- angiotensin-converting enzyme
- bioactive molecules
- glyceroglycolipids
- saganhaematenone
