JOURNAL 3628
Records of Natural Products
VOLUME & ISSUE
Year: 2026 Issue: 1
Year: 2026 Issue: 1
PAGES
p.6 - 6
p.6 - 6
STATISTICS
Viewed 101 times.
Viewed 101 times.
AUTHORS
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Gaolei Xi
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Qing-fu Wang
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Yong-zhen Zhao
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Chang-tong Lu
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Hao-yang Chen
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Liu-ke Zhang
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Yi-bo Ning
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Pengfei Yang
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Zhifei Chen
GRAPHICAL ABSTRACT
ABSTRACT
In our study, chemical exploration of the Nicotiana tabacum L. symbiotic fungus Aspergillus sp. TE-65L led to the discovery of a new himeic acid derivative, japonimeic acid J (1), along with two previously reported compounds 2 and 3. The structure of the new compound was unequivocally elucidated using nuclear magnetic resonance spectroscopy and high-resolution electrospray ionization mass spectrometry. Furthermore, compounds 1 and 2 displayed strong anti-phytopathogenic potency against Alternaria alternata and Botrytis cinerea, with a minimum inhibitory concentration of 4 μg/mL. This result suggests that they have considerable potential as new, naturally sourced agro-antibiotics for controlling fungal plant diseases.
KEYWORDS- symbiotic fungus
- natural product
- secondary metabolite
- himeic acids
- anti-phytopathogenic potency
