JOURNAL 1723


Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 4 October-December
PAGES
p.186 - 195
STATISTICS
Viewed 119 times.
AUTHORS
    B. Janardhan, V. Ravibabu , Peter. A. Crooks and B. Rajitha
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A series of poly substituted pyridines (3,11-disubstituted-7-aryl-5,6,8,9-tetrahydrodibenzo[c,h]acridines) were synthesized by the multicomponent condensation of 6-substituted-1-tetralone, aromatic aldehydes and ammonium acetate in ethanol using L-proline as an efficient organocatalyst. This methodology is mild, efficient, high yielding and the catalyst is inexpensive, easily recovered from the reaction mixture and reused for five times without losing its activity.

KEYWORDS
  • Multicomponent condensation
  • poly substituted pyridines
  • L-proline
  • 6-substituted-1-tetralone