JOURNAL 1722


Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 4 October-December
PAGES
p.179 - 185
STATISTICS
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AUTHORS
    Kamlesh R. Desale , Kamalakar P. Nandre and Shamkant L. Patil
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GRAPHICAL ABSTRACT


ABSTRACT


A highly efficient, green and expeditious method is described for the synthesis of substituted 2-amino2-chromenes employing one pot three component condensation of aromatic aldehydes, malononitrile and activated phenol in presence of p-dimethylaminopyridine (10 mol %) as a catalyst under microwave irradiation. The present method is operationally simple and offers many advantages such as high yield, short reaction time and simple workup.

KEYWORDS
  • 2-amino-2-chromenes
  • multicomponent
  • p-dimethylaminopyridine
  • microwave irradiation.