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3-Acyl(aroyl)coumarins as synthon in heterocyclic synthesis

Review Article

JOURNAL 1160

Organic Communications
VOLUME & ISSUE
Year: 2019 Issue: 2 April-June
PAGES
p.43 - 100
DOI ADDRESS
http://doi.org/10.25135/acg.oc.5619.02.1160
STATISTICS
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AUTHORS
  • Wafaa S. Hamama
  • Moged A. Berghot
  • Eman El Baz
  • Essam H. A. Hanashalshahaby
  • Moustafa Ahmed Gouda
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GRAPHICAL ABSTRACT

ABSTRACT

This review presents a systematic and comprehensive survey of the chemical reactivity of 3-acyl(aroyl) coumarins. The target compounds are important intermediates for the synthesis of a variety of synthetically useful and novel heterocyclic systems with different ring sizes such as isoxazole, pyrazole, 3H-triazolium salts, pyrimidine, pyridine, quinolone, benzoxocin, benzoxonin and benzoxepin.

 

 

 KEYWORDS
  • Coumarins
  • Pyrazoles
  • Thiazole
  • Pyridine
  • Heterocyclic
  • Reduction